Pre-validation of an in vitro skin irritation test for medical devices using the reconstructed human tissue model EpiDerm™
نویسندگان
چکیده
منابع مشابه
Skin Corrosion and Irritation Test of Nanoparticles Using Reconstructed Three-Dimensional Human Skin Model, EpiDermTM
Effects of nanoparticles (NPs) on skin corrosion and irritation using three-dimensional human skin models were investigated based on the test guidelines of Organization for Economic Co-operation and Development (OECD TG431 and TG439). EpiDermTM skin was incubated with NPs including those harboring iron (FeNPs), aluminum oxide (AlNPs), titanium oxide (TNPs), and silver (AgNPs) for a defined time...
متن کاملSkin corrosion and irritation test of sunscreen nanoparticles using reconstructed 3D human skin model
OBJECTIVES Effects of nanoparticles including zinc oxide nanoparticles, titanium oxide nanoparticles, and their mixtures on skin corrosion and irritation were investigated by using in vitro 3D human skin models (KeraSkin ((TM)) ) and the results were compared to those of an in vivo animal test. METHODS Skin models were incubated with nanoparticles for a definite time period and cell viability...
متن کاملEvaluation of a New Alternative to Primary Draize Skin Irritation Testing Using the EpiDermTM Skin Model
Correspondence : Michiru Genno, Technical Research Laboratory, Kurabo Industries Ltd., 14-5 Shimokidacho Neyagawa-shi, Osaka 572-0823, Japan. Tel.: +(81) 720 23 8800, Fax: +(81) 720 23 7906, E-mail: [email protected]
متن کاملReview Articles in Vitro Safety Testing Strategy for Skin Irritation Using the 3d Reconstructed Human Epidermis
One of the most recent trends in skin irritation safety testing of personal care and cosmetic products, discussed in detail in this review, is the use of reconstructed human epidermis models. Some of the commercially-available models have undergone a series of validation trials, which successfully advanced them as valuable tools for industry use. On a broader perspective, the 3D models are now ...
متن کاملstudy of cohesive devices in the textbook of english for the students of apsychology by rastegarpour
this study investigates the cohesive devices used in the textbook of english for the students of psychology. the research questions and hypotheses in the present study are based on what frequency and distribution of grammatical and lexical cohesive devices are. then, to answer the questions all grammatical and lexical cohesive devices in reading comprehension passages from 6 units of 21units th...
ذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Toxicology in Vitro
سال: 2018
ISSN: 0887-2333
DOI: 10.1016/j.tiv.2018.02.007